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Insights into the Sigma‐1 receptor Chaperone's cellular functions: A microarray report

9 Sept 2011

Abstract excerpt

We previously demonstrated that Sig-1Rs are critical regulators in neuronal morphogenesis and development via the regulation of oxidative stress and mitochondrial functions. In the present study, we sought to identify pathways and genes that are affected by Sig-1R. Gene expression profiles were examined in rat hippocampal neurons that had been cultured for 18 days in vitro (DIV). The cells were transduced with...

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PMID: 21905129
DOI: 10.1002/syn.20984

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