Article
Functional consequences of human lymphocyte cryopreservation: implications for subsequent interactions of cells with endothelium.
Journal of immunotherapy (Hagerstown, Md. : 1997) - 1 Oct 2011
Faint Jeff M, Tuncer Ceren, Garg Abhilok, Adams David H, Lalor Patricia F
Abstract excerpt
In order to understand human inflammatory diseases and to develop and assess new therapeutic strategies targeting leukocyte recruitment to tissue, it is necessary to study human lymphocyte interactions with endothelium. It is often not practical to carry out assays on fresh human samples and therefore cells may be cryopreserved and batched for later study. Furthermore, many forms of adoptive cell therapy use...
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