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Article

The phenotype of cryopreserved platelets influences the formation of platelet-leukocyte aggregates in an in vitro model.

Platelets - 1 Dec 2023

Winskel-Wood Ben, Padula Matthew P, Marks Denese C, Johnson Lacey

Abstract excerpt

Cryopreservation significantly alters the phenotype of platelets; generating distinct subpopulations, which may influence the formation of platelet leukocyte aggregates (PLA). PLAs are immunomodulatory and have been associated with transfusion-associated adverse events. As such, the aim of this study was to examine the effect of cryopreservation on the ability of platelets to form PLAs, using a monocyte-like cell...

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Identifiers

PMID: 37143347
DOI: 10.1080/09537104.2023.2206916

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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