Article
Identification of ionotrophic purinergic receptors in Huh-7 cells and their response towards structural proteins of HCV genotype 3a.
Virology journal - 8 Sept 2011
Manzoor Sobia, Idrees Muhammad, Ashraf Javed, Mehmood Azra, Butt Sadia, Fatima Kaneez, Akbar Haji, Rehaman Irshad U, Qadri Ishtiaq
Abstract excerpt
Hepatitis C virus (HCV) is a major health problem in developing countries including Pakistan. Chronic HCV infection results in progressive liver disease including fibrosis, cirrhosis, insulin resistance and eventually hepatocellular carcinoma (HCC). Ionotrophic purinergic (P2X) receptors are identified to involve in a spectrum of physiological and pathophysiological processes. However, the role of P2X receptors...
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