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Article

Receptor Tyrosine Kinase Pathway and Infiltrating Urothelial Carcinoma.

Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer - 1 Jan 2023

Buyucek Seyma, Coskun Sinem Kantarcioglu, Onal Binnur, Gamsizkan Mehmet, Cangur Sengul, Esbah Onur

Abstract excerpt

Receptor tyrosine kinase pathway is frequently searched for cancer causing mutations in tumors. Emerging targeted therapies are gleam of hope for them. Infiltrating urothelial carcinoma can have many morphological aspects according to their differentiation/variants. To evaluate KRAS, BRAF, and PIK3CA mutations and HER2, EGFR, and p16 expression, we divided urothelial carcinomas into two groups:...

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PMID: 36734953
DOI: 10.1615/JEnvironPatholToxicolOncol.2022044380

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