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Article

A novel TaulacZ allele reveals a requirement for Pitx2 in formation of the mammillothalamic tract.

Genesis (New York, N.Y. : 2000) - 1 Jan 2012

Skidmore Jennifer M, Waite Mindy R, Alvarez-Bolado Gonzalo, Puelles Luis, Martin Donna M

Abstract excerpt

The hypothalamic mammillary region is critical for spatial memory and vestibular processing. Pitx2 encodes a paired-like transcription factor that is highly expressed in the developing mammillary region and is required for subthalamic nucleus formation. Here we analyzed a loss of function Pitx2-TaulacZ knock-in allele to study the effects of Pitx2 deficiency on neuronal projections in the embryonic mammillary...

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PMID: 21898763
DOI: 10.1002/dvg.20793

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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