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Article

Catechol-O-methyltransferase genotype (Val158met) modulates cancer-related fatigue and pain sensitivity in breast cancer survivors.

Breast cancer research and treatment - 1 Jun 2012

Fernández-de-las-Peñas César, Fernández-Lao Carolina, Cantarero-Villanueva Irene, Ambite-Quesada Silvia, Rivas-Martínez Inés, del Moral-Avila Rosario, Arroyo-Morales Manuel

Abstract excerpt

Cancer-related fatigue and pain after surgery are the most frequent and most incapacitating cancer-related symptoms after breast cancer treatment. Genetic influence of cancer-related fatigue and pain has not been previously investigated. Our aim was to examine the influence of catechol-O-methyltransferase (COMT) Val158Met genotypes on cancer-related fatigue, post-mastectomy pain, and pressure pain...

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Source

Identifiers

PMID: 21898113
DOI: 10.1007/s10549-011-1757-y

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Catechol-O-methyltransferase genotype (Val158met) modulates cancer-related fatigue and pain sensitivity in breast cancer survivors.PMID 21898113Read ↗

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Association of COMT Val158Met polymorphism and breast cancer risk: an updated meta-analysis.Semantic proximity Read ↗

The Val158Met polymorphism of the human catechol-O-methyltransferase (COMT) gene may influence morphine requirements in cancer pain patients.Semantic proximity Read ↗

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