Article
Purification and characterization of the acetyl-CoA synthetase from Mycobacterium tuberculosis.
Acta biochimica et biophysica Sinica - 1 Nov 2011
Li Ru, Gu Jing, Chen Peng, Zhang Zhiping, Deng Jiaoyu, Zhang Xianen
Abstract excerpt
Acetyl-CoA (AcCoA) synthetase (Acs) catalyzes the conversion of acetate into AcCoA, which is involved in many catabolic and anabolic pathways. Although this enzyme has been studied for many years in many organisms, the properties of Mycobacterium tuberculosis Acs and the regulation of its activity remain unknown. Here, the putative acs gene of M. tuberculosis H37Rv (Mt-Acs) was expressed as a fusion protein with...
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