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Article

Quantitative expression of phospholipase C zeta, as an index to assess fertilization potential of a semen sample

6 Sept 2011

Abstract excerpt

BACKGROUND: Failed fertilization post-ICSI has been mainly attributed to the sperm's inability to induce oocyte activation. Phospholipase C zeta (PLCζ) is considered to be one of the factors for the induction of oocyte activation. The aim of this study was to quantitatively assess the expression of PLCζ in globozoospermic men or those with previously low or failed fertilization in comparison with fertile men or...

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PMID: 21896550
DOI: 10.1093/humrep/der285

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