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Article

Coatomer and dimeric ADP ribosylation factor 1 promote distinct steps in membrane scission.

The Journal of cell biology - 5 Sept 2011

Beck Rainer, Prinz Simone, Diestelkötter-Bachert Petra, Röhling Simone, Adolf Frank, Hoehner Kathrin, Welsch Sonja, Ronchi Paolo, Brügger Britta, Briggs John A G, Wieland Felix

Abstract excerpt

Formation of coated vesicles requires two striking manipulations of the lipid bilayer. First, membrane curvature is induced to drive bud formation. Second, a scission reaction at the bud neck releases the vesicle. Using a reconstituted system for COPI vesicle formation from purified components, we find that a dimerization-deficient Arf1 mutant, which does not display the ability to modulate membrane curvature in...

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Identifiers

PMID: 21893600
DOI: 10.1083/jcb.201011027
PMCID: PMC3171119

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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