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Article

Environmental pH changes, but not the LuxS signalling pathway, regulate SpeB expression in M1 group A streptococci.

Journal of medical microbiology - 1 Jan 2012

Chiang-Ni Chuan, Zheng Po-Xing, Tsai Pei-Jane, Chuang Woei-Jer, Lin Yee-Shin, Liu Ching-Chuan, Wu Jiunn-Jong

Abstract excerpt

The autoinducer-2/LuxS signalling pathway participates in quorum sensing in diverse bacterial species. In group A streptococci (GAS), LuxS has been shown to be involved in regulating the expression of several important virulence factors. Streptococcal pyrogenic exotoxin B (SpeB), a cysteine protease that has important roles in GAS pathogenesis, is positively regulated by LuxS in M3 and M5 strains. In the present...

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Identifiers

PMID: 21890514
DOI: 10.1099/jmm.0.036012-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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