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Article

[Phenotypic analysis of luxS gene deletion mutants and its application in virulence regulation research in group B Streptococcus].

Nan fang yi ke da xue xue bao = Journal of Southern Medical University - 1 Jan 2006

Ouyang Qian, Ma Wen-li, Liu Cui-hua, Shi Rong, Zheng Wen-ling

Abstract excerpt

OBJECTIVE: To explore the mechanism of virulence regulation in group B streptococcus (BGS) by studying LuxS-related AI-2 quorum-sensing pathway in GBS. METHODS: luxS gene deletion mutants of GBS (Delta lusX) were characterized by reverse transcription (RT)-PCR, colony immunoblot analysis, growth curve measurement, and cAMP determination. Functional analysis of luxS in the deletion mutants was conducted by...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 17133704

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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