Article
A reduced incidence of digestive disorders in rabbits is associated with allelic diversity at the TLR4 locus.
Veterinary immunology and immunopathology - 15 Dec 2011
Zhang Gong-Wei, Wang Hong-Ze, Chen Shi-Yi, Li Zi-Cheng, Zhang Wen-Xiu, Lai Song-Jia
Abstract excerpt
Toll-like receptor 4 (TLR4) plays a fundamental role in pathogen recognition and activation of host innate immunity. In this study, we detected five coding single-nucleotide polymorphisms (cSNPs) of the TLR4 gene in New Zealand White rabbits and analyzed their associations with genetic resistance...
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