Polymorphisms in IL10 are associated with total Immunoglobulin E levels and Schistosoma mansoni infection intensity in a Brazilian population.

doi:10.1038/gene.2010.50

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Polymorphisms in IL10 are associated with total Immunoglobulin E levels and Schistosoma mansoni infection intensity in a Brazilian population.

Genes and immunity - 1 Jan 2011

Grant A V, Araujo M I, Ponte E V, Oliveira R R, Cruz A A, Barnes K C, Beaty T H

Abstract excerpt

Interleukin (IL)-10 is a regulatory cytokine of the helper T cell type 2 (TH2) pathway, which underlies both the host defense to helminthic infection and atopic diseases, including asthma. Although IL10 promoter polymorphisms are associated with increased atopy risk, IL10 variation has not been thoroughly explored in schistosomiasis-endemic populations. Three atopy-related IL10 promoter polymorphisms (rs1800896,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged, 80 and over

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Brazil

Share to Immunoglobulin E

Share to Interleukin-10

Share to Promoter Regions, Genetic

Share to Schistosoma mansoni

Share to Schistosomiasis mansoni

Share to Young Adult

Source

Open in PubMed

Identifiers

PMID: 20927126
DOI: 10.1038/gene.2010.50

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polymorphisms in IL10 are associated with total Immunoglobulin E levels and Schistosoma mansoni infection intensity in a Brazilian population.PMID 20927126Read ↗

Functional polymorphisms in IL13 are protective against high Schistosoma mansoni infection intensity in a Brazilian population.Semantic proximity Read ↗

Interleukin-4 and STAT6 promoter polymorphisms but not interleukin-10 or 13 are essential for schistosomiasis and associated disease burden among Nigerian children.Semantic proximity Read ↗

Association of SNP (-G1082A) IL-10 with increase in severity of periportal fibrosis in schistosomiasis, in the northeast of Brazil.Semantic proximity Read ↗

The Genetics of Human Schistosomiasis Infection Intensity and Liver Disease: A Review.Semantic proximity Read ↗

Frequency distribution of cytokine and associated transcription factor single nucleotide polymorphisms in Zimbabweans: Impact on schistosome infection and cytokine levels.Semantic proximity Read ↗

Genetic epidemiology of human schistosomiasis in Brazil.Semantic proximity Read ↗

The landscape of human genes involved in the immune response to parasitic worms.Semantic proximity Read ↗

High Schistosoma mansoni infection intensity is associated with distinct gut microbiome and low levels of systemic cytokines in children along the Albert-Nile, Northern UgandaSemantic proximity Read ↗

Pathogenic Interleukin-10 Receptor Alpha Variants in Humans — Balancing Natural Selection and Clinical ImplicationsSemantic proximity Read ↗

A STAT6 gene polymorphism is associated with high infection levels in urinary schistosomiasis.Semantic proximity Read ↗

Associations of IL13 gene polymorphisms and immune factors with Schistosoma haematobium infection in schoolchildren in four schistosomiasis-endemic communities in Ghana.Semantic proximity Read ↗

Coassociations between IL10 polymorphisms, IL-10 production, helminth infection, and asthma/wheeze in an urban tropical population in Brazil.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.