Article
HLA-DRA polymorphisms associated with risk of nasal polyposis in asthmatic patients.
American journal of rhinology & allergy - 1 Jan 2000
Kim Jeong-Hyun, Park Byung-Lae, Cheong Hyun Sub, Pasaje Charisse Flerida A, Bae Joon Seol, Park Jong Sook, Uh Soo-Taek, Kim Yong-Hoon, Kim Mi-Kyeong, Choi Inseon S, Choi Byoung Whui, Park Choon-Sik, Shin Hyoung Doo
Abstract excerpt
BACKGROUND: Nasal polyps, part of the aspirin triad symptoms, are edematous protrusions arising from the mucosa of the nasal sinuses. Although the causative factors and pathogenesis of the polyps are unknown, the significant effect of human leukocyte antigen-DR (HLA-DR) expression in nasal polyps and genetic associations of the major histocompatibility complex class II, DR alpha (HLA-DRA) with immune-mediated...
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