Article
Genetic association analysis of CIITA variations with nasal polyp pathogenesis in asthmatic patients.
Molecular medicine reports - 1 Mar 2013
Bae Joon Seol, Pasaje Charisse Flerida A, Park Byung Lae, Cheong Hyun Sub, Kim Jeong-Hyun, Uh Soo-Taek, Park Choon-Sik, Shin Hyoung Doo
Abstract excerpt
Nasal polyps are abnormal lesions arising mainly from the nasal mucosa and paranasal sinuses. Since the human class II, major histocompatibility complex, transactivator (CIITA) is a positive regulator of class II, major histocompatibility complex gene transcription, the CIITA gene is thought to be involved in the presence of nasal polyps in asthma and aspirin...
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