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Article

Endogenous genotoxic agents and processes as a basis of spontaneous carcinogenesis.

Mutation research - 1 May 1990

Lutz W K

Abstract excerpt

A list of endogenous DNA-damaging agents and processes is given. Endogenous electrophiles are found with the cosubstrates of physiological transfer reactions (S-adenosylmethionine for methylation, ATP for phosphorylation, NAD+ for ADP-ribosylation, acetyl CoA for acetylation). Aldehyde groups (glyceraldehyde-3-phosphate, formaldehyde, open forms of reducing sugars, degradation products of peroxidation) or...

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PMID: 2188125
DOI: 10.1016/0165-1110(90)90020-c

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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