Article
Novel aspects of oxidative stress-associated carcinogenesis.
Antioxidants & redox signaling - 1 Jan 2000
Toyokuni Shinya
Abstract excerpt
Oxidative stress is associated with carcinogenesis. Reactive oxygen and nitrogen species contribute to the accumulation of mutations in the genome, presumably followed by selective processes. Recent data suggest that preferred signaling pathways exist for oxidative stress-associated carcinogenesis. Whether this completely depends on random mutations induced by reactive species or whether instead some fragile...
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