Article
A matrix metalloproteinase 9 (MMP9) gene single nucleotide polymorphism is associated with predisposition to tick-borne encephalitis virus-induced severe central nervous system disease.
Ticks and tick-borne diseases - 1 May 2018
Barkhash Andrey V, Yurchenko Andrey A, Yudin Nikolay S, Ignatieva Elena V, Kozlova Irina V, Borishchuk Inessa A, Pozdnyakova Larisa L, Voevoda Mikhail I, Romaschenko Aida G
Abstract excerpt
The progression of infectious diseases depends on causative agents, the environment and the host's genetic susceptibility. To date, human genetic susceptibility to tick-borne encephalitis (TBE) virus-induced disease has not been sufficiently studied. We have combined whole-exome sequencing with a candidate gene approach to identify genes that are involved in the development of predisposition to TBE in a Russian...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.