Article
Role of stochastic processes in maintaining discrete strain structure in antigenically diverse pathogen populations.
Proceedings of the National Academy of Sciences of the United States of America - 13 Sept 2011
Buckee Caroline O, Recker Mario, Watkins Eleanor R, Gupta Sunetra
Abstract excerpt
Many highly diverse pathogen populations appear to exist stably as discrete antigenic types despite evidence of genetic exchange. It has been shown that this may arise as a consequence of immune selection on pathogen populations, causing them to segregate permanently into discrete nonoverlapping subsets of antigenic variants to minimize competition for available hosts. However, discrete antigenic strain structure...
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