Article
Confirmation of association of the macrophage migration inhibitory factor gene with systemic sclerosis in a large European population.
Rheumatology (Oxford, England) - 1 Nov 2011
Bossini-Castillo Lara, Simeon Carmen P, Beretta Lorenzo, Vonk Madelon C, Callejas-Rubio José Luis, Espinosa Gerard, Carreira Patricia, Camps María T, Rodríguez-Rodríguez Luis, Rodríguez-Carballeira Mónica, García-Hernández Francisco J, López-Longo Francisco J, Hernández-Hernández Vanesa, Sáez-Comet Luis, Egurbide María Victoria, Hesselstrand Roger, Nordin Annika, Hoffmann-Vold Anna-Maria, Vanthuyne Marie, Smith Vanessa, De Langhe Ellen, Kreuter Alexander, Riemekasten Gabriela, Witte Torsten, Hunzelmann Nicolas, Voskuyl Alexandre E, Schuerwegh Annemie J, Lunardi Claudio, Airó Paolo, Scorza Raffaella, Shiels Paul, van Laar Jacob M, Fonseca Carmen, Denton Christopher, Herrick Ariane, Worthington Jane, Koeleman Bobby P, Rueda Blanca, Radstake Timothy R D J, Martin Javier
Abstract excerpt
OBJECTIVES: The aim of this study was to confirm the implication of macrophage migration inhibitory factor (MIF) gene in SSc susceptibility or clinical phenotypes in a large European population. METHODS: A total of 3800 SSc patients and 4282 healthy controls of white Caucasian ancestry from eight different European countries were included in the study. The MIF -173 single nucleotide polymorphism (SNP) was...
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