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Article

Host immunity and pathogen strain contribute to intestinal disaccharidase impairment following gut infection.

Journal of immunology (Baltimore, Md. : 1950) - 1 Oct 2011

Solaymani-Mohammadi Shahram, Singer Steven M

Abstract excerpt

Infection or other inflammatory insults in the small intestine often result in reduced disaccharidase enzyme levels. Using a mouse model of giardiasis, we examined the role of host immunity and pathogen virulence in mediating disaccharidase deficiency postinfection (p.i.). C57BL/6J mice were infected with two strains, WB and GS, of the human parasite Giardia duodenalis. The levels of sucrase, maltase, and lactase...

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Identifiers

PMID: 21873528
DOI: 10.4049/jimmunol.1100606
PMCID: PMC3178714

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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