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Article

CD40 C/T(-1) and CTLA-4 A/G(49) SNPs are associated with autoimmune thyroid diseases in the Chinese population.

Endocrine - 1 Feb 2012

Yang Jing, Qin Qiu, Yan Ni, Zhu Yuan-Feng, Li Cui, Yang Xiang-Ju, Wang Xuan, Pandey Madhu, Hou Peng, Zhang Jin-An

Abstract excerpt

This study was to investigate whether the common polymorphisms of CD40 and CTLA4 genes confer susceptibility to AITD in the Chinese population. A set of unrelated subjects including 303 GD patients, 208 HT patients, and 215 matched healthy controls were recruited. SNPs were genotyped by the method of PCR-RFLP. (1) As for CD40 C/T(-1) SNP, only a significant difference was found in allele frequencies between GD...

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Source

Identifiers

PMID: 21866398
DOI: 10.1007/s12020-011-9510-1

Genes

CTLA4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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