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Article

A C/T polymorphism in the 5' untranslated region of the CD40 gene is associated with later onset of Graves' disease in Japanese.

Endocrine journal - 1 Aug 2005

Mukai Tokunori, Hiromatsu Yuji, Fukutani Tomoka, Ichimura Michiko, Kaku Hiroo, Miyake Ikuyo, Yamada Kentaro

Abstract excerpt

Graves' disease (GD) is an autoimmune disorder with genetic predisposition. CD40, which stimulates lymphocyte proliferation and differentiation, is an important immunomodulator and is expressed in the thyroid follicular cells as well as antigen-presenting cells. A single nucleotide polymorphism (SNP) at position -1 of the Kozak sequence of the CD40 gene has been reported to be associated with the development of...

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Identifiers

PMID: 16127217
DOI: 10.1507/endocrj.52.471

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A C/T polymorphism in the 5' untranslated region of the CD40 gene is associated with later onset of Graves' disease in Japanese.PMID 16127217Read ↗

Association of a C/T single-nucleotide polymorphism in the 5' untranslated region of the CD40 gene with Graves' disease in Japanese.Semantic proximity Read ↗

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Role of Different CD40 Polymorphisms in Graves' Disease and Hashimoto's Thyroiditis.Semantic proximity Read ↗

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Compelling Evidence Linking CD40 Gene With Graves' Disease in the Chinese Han Population.Semantic proximity Read ↗

Association of CD40 gene polymorphism (C-1T) with susceptibility and phenotype of Graves' disease.Semantic proximity Read ↗

A C/T polymorphism in CD40 gene is not associated with susceptibility and phenotype of Graves' disease in Taiwanese.Semantic proximity Read ↗

A C/T single-nucleotide polymorphism in the region of the CD40 gene is associated with Graves' disease.Semantic proximity Read ↗

CD40 C/T-1 polymorphism plays different roles in Graves' disease and Hashimoto's thyroiditis: a meta-analysis.Semantic proximity Read ↗

A single nucleotide polymorphism in the CD40 gene on chromosome 20q (GD-2) provides no evidence for susceptibility to Graves' disease in UK Caucasians.Semantic proximity Read ↗

CD40 C/T(-1) and CTLA-4 A/G(49) SNPs are associated with autoimmune thyroid diseases in the Chinese population.Semantic proximity Read ↗

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