Article
On the causal interpretation of heritability from a structural causal modeling perspective.
Studies in history and philosophy of science - 1 Aug 2022
Lu Qiaoying, Bourrat Pierrick
Abstract excerpt
Heritability estimated using the analysis of variance (ANOVA) for ascribing causal responsibility to genes for a phenotype has been criticized widely. First, there are problems associated with articulating the exact causal meaning of heritability in the standard model. Second, in conditions of gene-environment interaction or covariation that violate the assumptions made by the standard model, a causal...
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