Biometric and developmental gene-environment interactions: looking back, moving forward.

Abstract excerpt

A history of research on gene-environment interaction (G x E) is provided in this article, revealing the fact that there have actually been two distinct concepts of G x E since the very origins of this research. R. A. Fisher introduced what I call the biometric concept of G x E (G x EB), whereas Lancelot Hogben introduced what I call the developmental concept of G x E (G x ED). Much of the subsequent history of...

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