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Article

Lentiviral Gene Transfer into the Dorsal Root Ganglion of Adult Rats

1 Jan 2011

Abstract excerpt

BACKGROUND: Lentivector-mediated gene delivery into the dorsal root ganglion (DRG) is a promising method for exploring pain pathophysiology and for genetic treatment of chronic neuropathic pain. In this study, a series of modified lentivector particles with different cellular promoters, envelope glycoproteins, and viral accessory proteins were generated to evaluate the requirements for efficient transduction into...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 21861915
DOI: 10.1186/1744-8069-7-63

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