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Article

Physiogenomic analysis of CYP450 drug metabolism correlates dyslipidemia with pharmacogenetic functional status in psychiatric patients.

Biomarkers in medicine - 1 Aug 2011

Ruaño Gualberto, Villagra David, Szarek Bonnie, Windemuth Andreas, Kocherla Mohan, Gorowski Krystyna, Berrezueta Christopher, Schwartz Harold I, Goethe John

Abstract excerpt

AIMS: To investigate associations between novel human cytochrome P450 (CYP450) combinatory (multigene) and substrate-specific drug metabolism indices, and elements of metabolic syndrome, such as low density lipoprotein cholesterol (LDLc), high density lipoprotein cholesterol (HDLc), triglycerides and BMI, using physiogenomic analysis. METHODS: CYP2C9, CYP2C19 and CYP2D6 genotypes and clinical data were obtained...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21861666
DOI: 10.2217/bmm.11.33
PMCID: PMC3225002

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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