Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Copy number variation in the complement factor H-related genes and age-related macular degeneration.

Molecular vision - 1 Jan 2011

Kubista Katharina E, Tosakulwong Nirubol, Wu Yanhong, Ryu Euijung, Roeder Jaime L, Hecker Laura A, Baratz Keith H, Brown William L, Edwards Albert O

Abstract excerpt

PURPOSE: To determine the contribution of copy number variation (CNV) in the regulation of complement activation (RCA) locus to the development of age-related macular degeneration (AMD). METHODS: A multiplex ligation-dependent probe amplification assay was developed to quantify the number of copi...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Apolipoproteins
Share to Blood Proteins
Share to Complement C3b Inactivator Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Complement Factor H

Share to DNA Probes

Share to Gene Dosage

Share to Macular Degeneration

Source

Open in PubMed Open full text

Identifiers

PMID: 21850184
PMCID: PMC3156785

Genes

CFHR1
CFHR3
CFH
CFHR2
CFHR4
CFHR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21850184-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Copy number variation in the complement factor H-related genes and age-related macular degeneration.PMID 21850184Read ↗

Contribution of copy number variation in the regulation of complement activation locus to development of age-related macular degeneration.Semantic proximity Read ↗

Comprehensive Analysis of Copy Number Variation of Genes at Chromosome 1 and 10 Loci Associated with Late Age Related Macular DegenerationSemantic proximity Read ↗

Extended haplotypes in the complement factor H (CFH) and CFH-related (CFHR) family of genes protect against age-related macular degeneration: characterization, ethnic distribution and evolutionary implications.Semantic proximity Read ↗

Genetic mechanisms and age-related macular degeneration: common variants, rare variants, copy number variations, epigenetics, and mitochondrial genetics.Semantic proximity Read ↗

Rare Variants in the Functional Domains of Complement Factor H Are Associated With Age-Related Macular Degeneration.Semantic proximity Read ↗

Association study of complement factor H, C2, CFB, and C3 and age-related macular degeneration in a Han Chinese population.Semantic proximity Read ↗

Multiallelic copy number variation in the complement component 4A (C4A) gene is associated with late-stage age-related macular degeneration (AMD).Semantic proximity Read ↗

Copy number variations in candidate genes in neovascular age-related macular degeneration.Semantic proximity Read ↗

Sequence and Expression of Complement Factor H Gene Cluster Variants and Their Roles in Age-Related Macular Degeneration Risk.Semantic proximity Read ↗

Genome-Wide Association Study Reveals Variants in CFH and CFHR4 Associated with Systemic Complement Activation: Implications in Age-Related Macular Degeneration.Semantic proximity Read ↗

Deletion of CFHR3 and CFHR1 genes in age-related macular degeneration.Semantic proximity Read ↗

Common haplotypes at the CFH locus and low-frequency variants in CFHR2 and CFHR5 associate with systemic FHR concentrations and age-related macular degeneration.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.