Article
Macro and micro diversity of Clostridium difficile isolates from diverse sources and geographical locations.
PloS one - 1 Jan 2012
Stabler Richard A, Dawson Lisa F, Valiente Esmeralda, Cairns Michelle D, Martin Melissa J, Donahue Elizabeth H, Riley Thomas V, Songer J Glenn, Kuijper Ed J, Dingle Kate E, Wren Brendan W
Abstract excerpt
Clostridium difficile has emerged rapidly as the leading cause of antibiotic-associated diarrheal disease, with the temporal and geographical appearance of dominant PCR ribotypes such as 017, 027 and 078. Despite this continued threat, we have a poor understanding of how or why particular variants emerge and the sources of strains that dominate different human populations. We have undertaken a breadth genotyping...
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