Article
Control of microvascular PO₂ kinetics following onset of muscle contractions: role for AMPK.
American journal of physiology. Regulatory, integrative and comparative physiology - 1 Nov 2011
Kano Yutaka, Poole David C, Sudo Mizuki, Hirachi Toshiro, Miura Shinji, Ezaki Osamu
Abstract excerpt
The microvascular partial pressure of oxygen (Pmv(o(2))) kinetics following the onset of exercise reflects the relationship between muscle O(2) delivery and uptake (Vo(2)). Although AMP-activated protein kinase (AMPK) is known as a regulator of mitochondria and nitric oxide metabolism, it is unclear whether the dynamic balance of O(2) delivery and Vo(2) at exercise onset is dependent on AMPK activation level. We...
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