Article
Rich regulates target specificity of photoreceptor cells and N-cadherin trafficking in the Drosophila visual system via Rab6.
Neuron - 11 Aug 2011
Tong Chao, Ohyama Tomoko, Tien An-Chi, Rajan Akhila, Haueter Claire M, Bellen Hugo J
Abstract excerpt
Neurons establish specific synaptic connections with their targets, a process that is highly regulated. Numerous cell adhesion molecules have been implicated in target recognition, but how these proteins are precisely trafficked and targeted is poorly understood. To identify components that affect synaptic specificity, we carried out a forward genetic screen in the Drosophila eye. We identified a gene, named ric1...
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