Article
Adhesive but not signaling activity of Drosophila N-cadherin is essential for target selection of photoreceptor afferents.
Developmental biology - 15 Apr 2007
Yonekura Shinichi, Xu Lei, Ting Chun-Yuan, Lee Chi-Hon
Abstract excerpt
Drosophila N-cadherin (CadN) is an evolutionarily conserved, atypical classical cadherin, which has a large complex extracellular domain and a catenin-binding cytoplasmic domain. We have previously shown that CadN regulates target selection of R7 photoreceptor axons. To determine the functional domains of CadN, we conducted a structure-function analysis focusing on its in vitro adhesive activity and in vivo...
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