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Article

Longevity pathways: HSF1 and FoxO pathways, a new therapeutic target to prevent age-related diseases.

Current aging science - 1 Jul 2012

Perez Felipe P, Moinuddin Syed S, ul ain Shamim Qurrat, Joseph Dennis J, Morisaki Jorge, Zhou Ximing

Abstract excerpt

Modern medicine is directed towards the prevention, detection and cure of individual diseases. Yet, current medical models inadequately describe aging-associated diseases. We now know that failure in longevity pathways including oxidative stress, multisystem dysregulation, inflammation, sarcopenia, protein deposition and atherosclerosis are associated with age-related diseases. Such longevity pathways are...

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Source

Identifiers

PMID: 21834787
DOI: 10.2174/1874609811205020087

Genes

HSF1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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