Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Role of the guanine nucleotide exchange factor Rom2 in cell wall integrity maintenance of Aspergillus fumigatus.

Eukaryotic cell - 1 Feb 2013

Samantaray Sweta, Neubauer Michael, Helmschrott Christoph, Wagener Johannes

Abstract excerpt

Aspergillus fumigatus is a mold and the causal agent of invasive aspergillosis, a systemic disease with high lethality. Recently, we identified and functionally characterized three stress sensors implicated in the cell wall integrity (CWI) signaling of this pathogen, namely, Wsc1, Wsc3, and MidA. Here, we functionally characterize Rom2, a guanine nucleotide exchange factor with essential function for the cell...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aspergillus fumigatus
Share to Caspofungin
Share to Drug Resistance, Fungal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Echinocandins

Share to Hyphae

Share to Lipopeptides

Share to rho GTP-Binding Proteins

Share to Spores, Fungal

Source

Open in PubMed Open full text

Identifiers

PMID: 23264643
DOI: 10.1128/EC.00246-12
PMCID: PMC3571289

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Role of the guanine nucleotide exchange factor Rom2 in cell wall integrity maintenance of Aspergillus fumigatus.PMID 23264643Read ↗

The Rho1 GTPase-activating protein CgBem2 is required for survival of azole stress in Candida glabrata.Semantic proximity Read ↗

Involvement of the Cell Wall–Integrity Pathway in Signal Recognition, Cell-Wall Biosynthesis, and Virulence in <i>Magnaporthe oryzae</i>Semantic proximity Read ↗

Cell Wall Integrity Pathway Involved in Morphogenesis, Virulence and Antifungal Susceptibility in Cryptococcus neoformansSemantic proximity Read ↗

Wsc1 and Mid2 are cell surface sensors for cell wall integrity signaling that act through Rom2, a guanine nucleotide exchange factor for Rho1.Semantic proximity Read ↗

The RAM Network in Pathogenic FungiSemantic proximity Read ↗

Aspergillus fumigatus calcium-responsive transcription factors regulate cell wall architecture promoting stress tolerance, virulence and caspofungin resistance.Semantic proximity Read ↗

Signaling through Lrg1, Rho1 and Pkc1 Governs Candida albicans Morphogenesis in Response to Diverse CuesSemantic proximity Read ↗

Rho2-dependent cell wall remodeling boosts the fungistatic activity of manogepix against <i>Aspergillus fumigatus</i>Semantic proximity Read ↗

<i>Aspergillus fumigatus</i> G-protein coupled receptors GprM and GprJ are important for the regulation of the cell wall integrity pathway, secondary metabolite production, and virulenceSemantic proximity Read ↗

Cell Wall Integrity and Its Industrial Applications in Filamentous FungiSemantic proximity Read ↗

Rho1 has distinct functions in morphogenesis, cell wall biosynthesis and virulence of Fusarium oxysporum.Semantic proximity Read ↗

GDP-mannose pyrophosphorylase is essential for cell wall integrity, morphogenesis and viability of Aspergillus fumigatus.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.