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Article

Genome-wide association analysis of incident coronary heart disease (CHD) in African Americans: a short report.

PLoS genetics - 1 Aug 2011

Barbalic Maja, Reiner Alex P, Wu Chunyuan, Hixson James E, Franceschini Nora, Eaton Charles B, Heiss Gerardo, Couper David, Mosley Thomas, Boerwinkle Eric

Abstract excerpt

African Americans have the highest rate of mortality due to coronary heart disease (CHD). Although multiple loci have been identified influencing CHD risk in European-Americans using a genome-wide association (GWAS) approach, no GWAS of incident CHD has been reported for African Americans. We performed a GWAS for incident CHD events collected during 19 years of follow-up in 2,905 African Americans from the...

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PMID: 21829389
DOI: 10.1371/journal.pgen.1002199
PMCID: PMC3150445

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