Article
Heritability and familiality of type 2 diabetes and related quantitative traits in the Botnia Study.
Diabetologia - 1 Nov 2011
Almgren P, Lehtovirta M, Isomaa B, Sarelin L, Taskinen M R, Lyssenko V, Tuomi T, Groop L
Abstract excerpt
AIMS/HYPOTHESIS: To study the heritability and familiality of type 2 diabetes and related quantitative traits in families from the Botnia Study in Finland. METHODS: Heritability estimates for type 2 diabetes adjusted for sex, age and BMI are provided for different age groups of type 2 diabetes and for 34 clinical and metabolic traits in 5,810 individuals from 942 families using a variance component model (SOLAR)....
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