Article
Evidence that BMI and type 2 diabetes share only a minor fraction of genetic variance: a follow-up study of 23,585 monozygotic and dizygotic twins from the Finnish Twin Cohort Study.
Diabetologia - 1 Jul 2010
Lehtovirta M, Pietiläinen K H, Levälahti E, Heikkilä K, Groop L, Silventoinen K, Koskenvuo M, Kaprio J
Abstract excerpt
AIMS/HYPOTHESIS: We investigated whether BMI predicts type 2 diabetes in twins and to what extent that is explained by common genetic factors. METHODS: This was a population-based twin cohort study. Monozygotic (n = 4,076) and dizygotic (n = 9,109) non-diabetic twin pairs born before 1958 answered a questionnaire in 1975, from which BMI was obtained. Information on incident cases of diabetes was obtained by...
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