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Association between parental history of diabetes and type 2 diabetes genetic risk scores in the PPP-Botnia and Framingham Offspring Studies.

Diabetes research and clinical practice - 1 Aug 2011

Vassy Jason L, Shrader Peter, Jonsson Anna, Fox Caroline S, Lyssenko Valeriya, Isomaa Bo, Groop Leif, Meigs James B, Franks Paul W

Abstract excerpt

OBJECTIVE: Parental history of diabetes and specific gene variants are risk factors for type 2 diabetes, but the extent to which these factors are associated is unknown. METHODS: We examined the association between parental history of diabetes and a type 2 diabetes genetic risk score (GRS) in two cohort studies from Finland (population-based PPP-Botnia study) and the US (family-based Framingham Offspring Study)....

Topics

Adult
Cohort Studies
Diabetes Mellitus
Diabetes Mellitus, Type 2
Finland
Genetic Predisposition to Disease
Humans
Life Style
Medical History Taking
Middle Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Parents

Risk Factors

United States

Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 21570145
DOI: 10.1016/j.diabres.2011.04.013
PMCID: PMC3156338

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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