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Article

HIF-1α is involved in mediating apoptosis resistance to Chlamydia trachomatis-infected cells

8 Aug 2011

Abstract excerpt

Chlamydiae are obligate intracellular Gram-negative bacteria that cause widespread diseases in humans. Due to the intimate association between bacterium and host, Chlamydia evolved various strategies to protect their host cell against death-inducing stimuli, allowing the bacterium to complete its development cycle. An RNA interference (RNAi)-based screen was used to identify host cell factors required for...

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PMID: 21824245
DOI: 10.1111/j.1462-5822.2011.01642.x

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