Article
<i>Chlamydia pneumoniae</i>directly interferes with HIF-1α stabilization in human host cells
10 May 2007
Abstract excerpt
Chlamydiaceae are obligate intracellular bacteria that cause endemic trachoma, sexually transmitted diseases and respiratory infections. The course of the diseases is determined by local inflammatory immune responses and the propensity of the pathogen to replicate within infected host cells. Both features require energy which is inseparably coupled to oxygen availability in the microenvironment. Hypoxia-inducible...
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