Article
Chlamydia preserves the mitochondrial network necessary for replication via microRNA-dependent inhibition of fission
22 Mar 2017
Abstract excerpt
Obligate intracellular bacteria such as Chlamydia trachomatis depend on metabolites of the host cell and thus protect their sole replication niche by interfering with the host cells’ stress response. Here, we investigated the involvement of host microRNAs (miRNAs) in maintaining the viability of C. trachomatis–infected primary human cells. We identified miR-30c-5p as a prominently up-regulated miRNA required for...
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