Article
Recent success in the discovery of coronary artery disease genes.
Canadian journal of physiology and pharmacology - 1 Aug 2011
Roberts Robert, Chen Li, Wells George A, Stewart Alexandre F R
Abstract excerpt
For more than 50 years, epidemiological studies have indicated that genetic predisposition accounts for approximately 50% of the susceptibility to coronary artery disease (CAD) and its sequelae, including myocardial infarction. Since common diseases such as CAD are caused by multiple genes, the age-old method of linkage analysis used to map monogenic Mendelian disorders in families unfortunately lacks the...
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