Article
Mechanisms governing the selection of translation initiation sites on foot-and-mouth disease virus RNA.
Journal of virology - 1 Oct 2011
Pöyry Tuija A A, Jackson Richard J
Abstract excerpt
Translation initiation dependent on the foot-and-mouth disease virus (FMDV) internal ribosome entry site (IRES) occurs at two sites (Lab and Lb), 84 nucleotides (nt) apart. In vitro translation of an mRNA comprising the IRES and Lab-Lb intervening segment fused to a chloramphenicol acetyltransferase (CAT) reporter has been used to study the parameters influencing the ratio of the two products and the combined...
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