Article
Thrombotic microangiopathy mimicking membranoproliferative glomerulonephritis.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association - 1 Oct 2011
Brackman Damien, Sartz Lisa, Leh Sabine, Kristoffersson Ann-Charlotte, Bjerre Anna, Tati Ramesh, Frémeaux-Bacchi Veronique, Karpman Diana
Abstract excerpt
A 4-year-old boy presented with proteinuria and developed progressive renal failure over 6 years. In the patient's family, five individuals were affected with atypical haemolytic uraemic syndrome (aHUS) but not the patient. Renal biopsies (n = 3) showed glomerular basement membrane thickening with double contours, endothelial swelling and deposits of C3 and C1q. Electron microscopy revealed mesangial and...
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