Article
A new class of lysosomal/vacuolar protein sorting signals.
The Journal of biological chemistry - 5 Apr 1990
Klionsky D J, Emr S D
Abstract excerpt
A number of inherited lysosomal diseases are known to result from missorting of lysosomal proteins. Considerable attention has been directed toward an understanding of this sorting pathway, and it has become apparent that different mechanisms are used for the sorting of lysosomal membrane and sol...
Topics
- Alkaline Phosphatase
- Amino Acid Sequence
- Biological Transport
- Electrophoresis, Polyacrylamide Gel
- Genes, Fungal
- Glycoside Hydrolases
- Glycosylation
- Immunosorbent Techniques
- Intracellular Membranes
- Lysosomes
- Membrane Proteins
- Molecular Sequence Data
- Mutation
- Recombinant Fusion Proteins
- Saccharomyces cerevisiae
- Signal Transduction
- Vacuoles
- beta-Fructofuranosidase
