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Article

A new class of lysosomal/vacuolar protein sorting signals.

The Journal of biological chemistry - 5 Apr 1990

Klionsky D J, Emr S D

Abstract excerpt

A number of inherited lysosomal diseases are known to result from missorting of lysosomal proteins. Considerable attention has been directed toward an understanding of this sorting pathway, and it has become apparent that different mechanisms are used for the sorting of lysosomal membrane and soluble proteins. Protein sorting to the yeast vacuole/lysosome provides a simple model system to study this process. We...

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PMID: 2180925

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