Article
Tiotropium is noninferior to salmeterol in maintaining improved lung function in B16-Arg/Arg patients with asthma.
The Journal of allergy and clinical immunology - 1 Aug 2011
Bateman Eric D, Kornmann Oliver, Schmidt Peter, Pivovarova Anna, Engel Michael, Fabbri Leonardo M
Abstract excerpt
BACKGROUND: The efficacy and safety of inhaled long-acting β(2)-adrenergic agonists in asthmatic patients with the B16-Arg/Arg genotype has been questioned, and the use of antimuscarinics has been proposed as an alternative in patients whose symptoms are not controlled by inhaled corticosteroids (ICSs). OBJECTIVE: We compared the efficacy and safety of the long-acting anticholinergic tiotropium with salmeterol...
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