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Article

Pharmacogenetics of calcineurin inhibitors in Brazilian renal transplant patients.

Pharmacogenomics - 1 Sept 2011

Santoro Ana, Felipe Claudia R, Tedesco-Silva Helio, Medina-Pestana Jose O, Struchiner Claudio J, Ojopi Elida B, Suarez-Kurtz Guilherme

Abstract excerpt

AIM: Polymorphisms in the CYP3A5 and ABCB1 genes have been investigated as modulators of the pharmacokinetics and clinical effects of cyclosporine (CSA) and tacrolimus (TAC) in European, North American and Asian populations, with controversial results. The extensive variation in worldwide frequen...

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Source

Identifiers

PMID: 21806386
DOI: 10.2217/pgs.11.70

Genes

ABCB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Prepared record publication-21806386-2026-09-05.1. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 5 Sept 2026.

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