Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Plasma Contact System 2.0

1 Jun 2011

Abstract excerpt

The contact system is a protease cascade that is initiated by factor XII activation on cardiovascular cells. The system starts procoagulant and proinflammatory reactions, via the intrinsic pathway of coagulation and the kallikrein-kinin system, respectively. The biochemistry of the contact system in vitro is well understood. However, activators of the system in vivo and their contributions to disease states have...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blood Coagulation and Thrombosis Mechanisms
Share to Coagulation, Bradykinin, Polyphosphates, and Angioedema
Share to Vitamin K Research Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 21805443
DOI: 10.1055/s-0031-1276586

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Plasma Contact System 2.0PMID 21805443Read ↗

In vivo activation and functions of the protease factor XIISemantic proximity Read ↗

Recent insights into the role of the contact pathway in thrombo-inflammatory disorders.Semantic proximity Read ↗

Factor XII as a Therapeutic Target in Thromboembolic and Inflammatory Diseases.Semantic proximity Read ↗

Coagulation and complement: Key innate defense participants in a seamless webSemantic proximity Read ↗

Hereditary angioedema: the plasma contact system out of control.Semantic proximity Read ↗

Dangerous liaisons: complement, coagulation, and kallikrein/kinin cross‐talk act as a linchpin in the events leading to thromboinflammationSemantic proximity Read ↗

Complement-coagulation connectionsSemantic proximity Read ↗

The blood coagulation system as a molecular machine.Semantic proximity Read ↗

Mechanisms of Immunothrombosis by SARS-CoV-2Semantic proximity Read ↗

Interactions between Coagulation and InflammationSemantic proximity Read ↗

The protein C pathwaysSemantic proximity Read ↗

Identification of the factor XII contact activation site enables sensitive coagulation diagnostics.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.