Article
A minD mutant of enterohemorrhagic E. coli O157:H7 has reduced adherence to human epithelial cells.
Microbial pathogenesis - 1 Nov 2011
Parti Rajinder P, Biswas Debabrata, Wang Monica, Liao Mingmin, Dillon Jo-Anne R
Abstract excerpt
Adherence to epithelial cells is a prerequisite for intestinal colonization by the bacterial pathogen, enterohemorrhagic Escherichia coli (EHEC). The deletion of minD, a cell division gene, in EHEC caused reduced adherence to human epithelioid cervical carcinoma (HeLa) and human colonic adenocarcinoma (Caco-2) cells as compared to wild-type. The minD mutant formed minicells and filaments owing to aberrant...
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